A Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis
| Status: | Completed |
|---|---|
| Conditions: | Psoriasis |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 18 - 75 |
| Updated: | 3/28/2019 |
| Start Date: | October 2008 |
| End Date: | April 2009 |
A Double-Blind, Randomized, Vehicle-Controlled Dose Ranging Study of the Effect of Ruxolitinib Phosphate Cream When Applied to Patients With Plaque Psoriasis
The study will be a double-blind, randomized, vehicle-controlled study with application of
ruxolitinib phosphate cream or vehicle in patients with stable plaque psoriasis. Application
will be QD for 12 weeks without occlusive dressings. There will be 4 treatments of 50
subjects each.
ruxolitinib phosphate cream or vehicle in patients with stable plaque psoriasis. Application
will be QD for 12 weeks without occlusive dressings. There will be 4 treatments of 50
subjects each.
Inclusion Criteria:
- Plaque psoriasis involving up to 2 to 20% Body Surface Area
Exclusion Criteria:
- Lesions solely involving intertriginious areas, the scalp or the face
- Systemic therapy for their psoriasis
- Pustular psoriasis or erythroderma
- Currently on other topical agents or UVB therapy within 2 weeks of the first dose of
study medication
- Started or discontinued therapy within 2 months of Screening with agents that can
exacerbate psoriasis
- Receiving systemic triazole antifungals except fluconazole
We found this trial at
28
sites
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials