Pre-operative Evaluation of Kidney & Pancreas Transplant Patients



Status:Completed
Conditions:Renal Impairment / Chronic Kidney Disease
Therapuetic Areas:Nephrology / Urology
Healthy:No
Age Range:19 - Any
Updated:11/3/2018
Start Date:April 2003
End Date:April 2012

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The Analysis of Data Collected During Angiography and Dobutamine Stress Contrast Echocardiograms in the Pre-Evaluation of Kidney and Pancreas Transplant Patients

Examine the clinical utility of the dobutamine stress contrast echoes and angiograms obtained
routinely in the evaluation of patients prior to kidney or pancreas transplantation.

Although there is an increasing quantity of data demonstrating the value of stress echo in
risk stratifying patients for cardiac risk prior to major non-cardiac surgery, the current
clinical practice utilized for assessing patients being evaluated for kidney or pancreas
transplantation is both a stress echocardiogram and a coronary angiogram. This gap in opinion
appears to be a concern on the part of both nephrologists, endocrinologists, and surgeons
that the stress echocardiogram may miss significant angiographic disease that could result in
major post-operative complications in this high-risk subgroup of patients (unstable angina,
non-fatal infarction, or death).

Inclusion Criteria:

- Patients who are being evaluated for a kidney and or pancreas transplant and scheduled
for a dobutamine stress echocardiogram and a coronary angiogram will be eligible to
participate

Exclusion Criteria:

- Patients with unstable angina at the time of their evaluation, or who have a severe
underlying cardiomyopathy or valve disease will be excluded.
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