Predictors of De-novo Development of Obstructive Sleep Apnea in Pregnancy
| Status: | Recruiting |
|---|---|
| Conditions: | Insomnia Sleep Studies, Obesity Weight Loss, Women's Studies, Pulmonary, Pulmonary |
| Therapuetic Areas: | Endocrinology, Psychiatry / Psychology, Pulmonary / Respiratory Diseases, Reproductive |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/9/2019 |
| Start Date: | November 2016 |
| End Date: | July 2020 |
| Contact: | Tamara Sequeira, RN |
| Email: | tsequeira@lifespan.org |
| Phone: | 401-793-3883 |
This study seeks to understand the physical, physiologic and biologic features that
predispose a woman to the development of obstructive sleep apnea once they are exposed to the
cardiopulmonary and metabolic physiological changes of pregnancy. Knowing these specific
predictive factors can help identify a population at risk and guide clinicians to develop
suitable targeting screening strategies.
predispose a woman to the development of obstructive sleep apnea once they are exposed to the
cardiopulmonary and metabolic physiological changes of pregnancy. Knowing these specific
predictive factors can help identify a population at risk and guide clinicians to develop
suitable targeting screening strategies.
Patients will be recruited from multiple community and hospital-based practices that care for
pregnant women. Subjects will have:
1. measurements of body composition
2. anthropometric measures
3. sleep and mood questionnaires
4. Home sleep studies
5. blood testing for biological markers
6. salivary testing for hormonal markers
7. pulmonary function tests and upper airway patency measurements
Women without sleep apnea at enrollment will then be followed longitudinally for the
development of obstructive sleep apnea during pregnancy with repeat assessment during their
third trimester. Women diagnosed with sleep apnea at enrollment will have no further
assessment in late pregnancy.
Monetary incentives will also be issued at data collection points. Subjects will receive
small gift incentives such as baby-related items.
pregnant women. Subjects will have:
1. measurements of body composition
2. anthropometric measures
3. sleep and mood questionnaires
4. Home sleep studies
5. blood testing for biological markers
6. salivary testing for hormonal markers
7. pulmonary function tests and upper airway patency measurements
Women without sleep apnea at enrollment will then be followed longitudinally for the
development of obstructive sleep apnea during pregnancy with repeat assessment during their
third trimester. Women diagnosed with sleep apnea at enrollment will have no further
assessment in late pregnancy.
Monetary incentives will also be issued at data collection points. Subjects will receive
small gift incentives such as baby-related items.
Inclusion Criteria:
- <13 completed weeks of gestation
- BMI >30 kg/m2 at recruitment
- >18 years of age
- Ability to give informed consent
Exclusion Criteria:
- Unable to meet inclusion criteria
- Twin pregnancies
We found this trial at
1
site
Miriam Hospital The Miriam Hospital is a private, not-for-profit hospital, with a history of providing...
Click here to add this to my saved trials
