Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Gastrointestinal, Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 4/6/2019 |
| Start Date: | October 2009 |
| End Date: | November 2020 |
Relative Abundance and Spatial Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)
Nonalcoholic fatty liver disease (NAFLD) is the most common type of liver disease in the
United States. The incidence of NAFLD is very similar to that of obesity, type 2 diabetes,
and the metabolic syndrome. The investigators hypothesize that there may be a relationship
between over-nutrition, decreased physical activity and the development of fatty liver. The
purpose of this study is to identify the types of fats and proteins, and the quantity of
each, that are associated with increased severity of NAFLD.
United States. The incidence of NAFLD is very similar to that of obesity, type 2 diabetes,
and the metabolic syndrome. The investigators hypothesize that there may be a relationship
between over-nutrition, decreased physical activity and the development of fatty liver. The
purpose of this study is to identify the types of fats and proteins, and the quantity of
each, that are associated with increased severity of NAFLD.
Inclusion Criteria:
- 18-65 year of age
- Undergoing elective abdominal or bariatric surgery
- May have normal or elevated ALT/AST levels
Exclusion Criteria:
- Presence of viral hepatitis
- Significant alcohol use
- Intercurrent infections
- Use of any thiazolidinediones
We found this trial at
1
site
1211 Medical Center Dr
Nashville, Tennessee 37232
Nashville, Tennessee 37232
(615) 322-5000
Vanderbilt Univ Med Ctr Vanderbilt University Medical Center (VUMC) is a comprehensive healthcare facility dedicated...
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