Effectiveness of a Developmental Reciprocity Treatment Program in Autism

Inclusion Criteria:

- Diagnosis of Autism Spectrum Disorder based on Autism Diagnostic Interview Revised
(ADI-R), Autism Diagnostic Observation Schedule (ADOS-2), DSM-5, and expert clinical
opinion;

- Males and females in good medical health between 2.0 and 5 years 11 months;

- Ability to participate in the testing procedures to the extent that valid standard
scores can be obtained;

- Stable treatment (e.g., applied behavior analysis), speech therapy, psychotropic
medication(s) or biomedical intervention(s) for at least 1 month prior to baseline
measurements with no anticipated changes during study participation;

- Availability of at least one English-speaking parent who can consistently participate
in parent training and research measures;

- Clinical Global Impression(CGI) Severity Social Interaction and Communication
Integrated Subscale ≥4;

- Meet the cutoff for Autism on the ADOS-2.

Exclusion Criteria:

- Current or lifetime diagnosis of severe psychiatric disorder (e.g., bipolar disorder,
etc.);

- A well-established genetic syndrome, such as Fragile X;

- Presence of active medical problem (e.g., unstable seizure disorder or heart disease);

- Child's primary language other than English;

- Previous adequate trial or training of a developmentally based intervention;

- Participants living more than 45 miles from Stanford University;

- Children with more than 20 hours of in-home ABA;

- At least one room of the house must be available to be dedicated to treatment during
session times;

- There must be no serious health and safety risks present in the home environment;

- The research team has the right to refuse to perform sessions in-home even if the
criteria above are met.