Ear Acupuncture During Chemotherapy Infusion for Breast Cancer, a Feasibility Study

Chemotherapy drugs used to treat cancer can cause many symptoms. Some of the most common
symptoms of receiving chemotherapy are nausea, vomiting, and anxiety. These symptoms can
affect the quality of life of cancer patients. Medications can help ease these, but many
patients continue to experience symptoms despite these treatments.

Acupuncture has been studied in clinical trials in cancer patients and has been shown to be
helpful for management of pain, nerve damage from chemotherapy, and nausea.

Ear acupuncture is a type of acupuncture that involves the stimulation of points on the
external ear. A few studies have suggested that ear acupuncture may help to reduce symptoms
of nausea and anxiety during chemotherapy.

This study is being done to evaluate the potential benefits of using ear acupuncture to
reduce symptoms like nausea and anxiety for women receiving chemotherapy for breast cancer.

Inclusion Criteria:

- History of histologically or cytologically proven Stage I-III breast cancer receiving
intravenous chemotherapy on an every 14 days or every 21 days schedule

- Age ≥ 18 years

- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1

- Signed informed consent

Exclusion Criteria:

- Receiving weekly chemotherapy

- Unstable cardiac disease or myocardial infarction within 6 months prior to study entry

- Uncontrolled seizure disorder

- Pregnancy or potential pregnancy

- Active clinically significant uncontrolled infection

- Prior use of acupuncture within 3 months prior to the study entry

- Uncontrolled major psychiatric disorders, such as major depression or psychosis

- Metastatic breast or other cancer