Exercise Intervention in Liver Transplant Patients
| Status: | Recruiting |
|---|---|
| Conditions: | Orthopedic, Gastrointestinal, Gastrointestinal |
| Therapuetic Areas: | Gastroenterology, Orthopedics / Podiatry |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/16/2019 |
| Start Date: | July 2016 |
| End Date: | December 2019 |
| Contact: | Jennifer C Lai, MD, MBA |
| Email: | jennifer.lai@ucsf.edu |
| Phone: | 415-476-2777 |
The purpose of this study is to learn more about the effects of exercise on functional status
and outcomes on patients with end-stage liver disease on the liver transplant waiting list
and who have undergone liver transplantation.
and outcomes on patients with end-stage liver disease on the liver transplant waiting list
and who have undergone liver transplantation.
This study aims to evaluate the effects of a home-based exercise intervention on outcomes in
liver transplant candidates and recipients. This home-based intervention consists of a
30-minute exercise session available on digital video disc or on the internet. This
intervention was originally developed to improve functional status in community-dwelling
older adults and therefore, has been designed to maximize the safety for even the most frail
individuals. Subjects enrolled in this study will be randomized to one of two arms: (a) the
exercise intervention arm in which the subjects will be asked perform this exercise session
three to four times per week or (b) the standard-of-care arm in which the patient will be
encouraged to exercise by their transplant clinician at every clinic visit. Subjects in the
exercise intervention arm will undergo this intervention for 6 months. All subjects will be
followed for up to two years from the time of enrollment to ascertain outcomes.
liver transplant candidates and recipients. This home-based intervention consists of a
30-minute exercise session available on digital video disc or on the internet. This
intervention was originally developed to improve functional status in community-dwelling
older adults and therefore, has been designed to maximize the safety for even the most frail
individuals. Subjects enrolled in this study will be randomized to one of two arms: (a) the
exercise intervention arm in which the subjects will be asked perform this exercise session
three to four times per week or (b) the standard-of-care arm in which the patient will be
encouraged to exercise by their transplant clinician at every clinic visit. Subjects in the
exercise intervention arm will undergo this intervention for 6 months. All subjects will be
followed for up to two years from the time of enrollment to ascertain outcomes.
Inclusion Criteria:
- Adult (>=18 years of age)
- Listed for liver transplantation or post-liver transplantation
- English speaking
Exclusion Criteria:
- Contraindications to weight-bearing exercise
- Non-English speaking
- Requires an assistive device for ambulation
- Active hepatic encephalopathy at the time of baseline assessment for enrollment in the
study
We found this trial at
3
sites
Duke University Younger than most other prestigious U.S. research universities, Duke University consistently ranks among...
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Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
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San Francisco, California 94143
Principal Investigator: Jennifer Lai, MD, MBA
Phone: 415-476-2777
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