Vitamin D Receptor Polymorphisms and Non-Melanoma Skin Cancer Risk
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Skin Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 50 - Any |
| Updated: | 7/5/2018 |
| Start Date: | October 31, 2012 |
| End Date: | June 6, 2019 |
Vitamin D Receptor Polymorphisms and Non-Melanoma Skin Cancer Risks in Alabama Population
The purpose of this study is to discover whether certain Vitamin D Receptor (VDR) gene
polymorphisms are associated with an increased risk of cutaneous basal cell carcinoma (BCC)
and/or cutaneous squamous cell carcinoma (SCC) in an Alabama population. Participant
demographic information such as physical characteristics (e.g., ethnicity), family history,
and cancer diagnosis will be collected in order to determine if there are relationships
between the gene polymorphisms, cancer diagnosis, and these characteristics.
polymorphisms are associated with an increased risk of cutaneous basal cell carcinoma (BCC)
and/or cutaneous squamous cell carcinoma (SCC) in an Alabama population. Participant
demographic information such as physical characteristics (e.g., ethnicity), family history,
and cancer diagnosis will be collected in order to determine if there are relationships
between the gene polymorphisms, cancer diagnosis, and these characteristics.
Inclusion Criteria:
- Patients with non-melanoma skin cancer (cases)
- Patients without non-melanoma skin cancer or history of non-melanoma skin cancer
(controls)
- Age 50 and older
- Native English speakers
- Patients at Kirklin Clinic
Exclusion Criteria:
- Age less than 50
- Diagnosis of melanoma or other type of cancer
- Non-English speakers
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