Self Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis

Inclusion Criteria:

- have self-reported unilateral or bilateral knee OA pain, according to American College
of Rheumatology criteria

- have had knee OA pain in the past 3 months with an average of at least 3 on a 10 cm
Visual Analog Scale (VAS) for pain

- can speak and read English

- have a device with internet access that can be used for secure video conferencing for
real-time remote supervision

- have access to a distraction-free, well lit, clean environment with a safe area to
store the device and device kit

- have no plan to change medication regimens for pain throughout the trial

- are able to travel to the coordinating center

- are willing and able to provide written informed consent prior to enrollment.

Exclusion Criteria:

- previous prosthetic knee replacement or non-arthroscopic surgery to the affected knee

- history of brain surgery, tumor, seizure, stroke, or intracranial metal implantation

- systemic rheumatic disorders, including rheumatoid arthritis, systemic lupus
erythematosus, and fibromyalgia

- uncontrolled hypertension (i.e., systolic blood pressure/ diastolic blood pressure ≥
150/95 mm Hg)

- heart failure

- history of acute myocardial infarction

- peripheral neuropathy

- alcohol/substance abuse

- cognitive impairment (i.e., Mini-Mental Status Exam score ≤ 23)

- pregnancy or lactation

- hospitalization within the preceding year for psychiatric illness