A Novel Lung Function Imaging Modality as a Preoperative Evaluation Tool (LIME)

To evaluate the correlation between pre-surgical 4-Dimensional Computed
Tomography-ventilation (4DCT-ventilation) imaging and post-surgical lung function. To
determine whether 4DCT-ventilation is a better predictor of post-surgical lung function than
nuclear medicine imaging using pulmonary function tests (PFTs). To determine whether
4DCT-ventilation is a better predictor of post-surgical lung function than nuclear medicine
imaging using quality of life (QOL) questionnaires. Evaluate cost-effectiveness of using
4DCT-ventialtion and VQ scans for pre-surgical assessment. To use longitudinal (pre and
post-surgical) 4DCT-ventilation imaging to derive novel post-surgical prediction formulas.

Inclusion Criteria:

1. Provision to sign and date the consent form.

2. Stated willingness to comply with all required (non-optional) study procedures and be
available for the duration of the study.

3. Be a male or female aged 18 to 100.

4. Patient with lung cancer (presumed or biopsy proven) undergoing evaluation for
resection.

5. Lung function assessment required for pre-surgical evaluation at the discretion of the
cardiothoracic surgeon.

6. Life expectancy greater than 3 months.

Exclusion Criteria:

1. Patients getting a planned wedge resection as the only thoracic resectional procedure.