Pain After Laparoscopic Cholecystectomy
| Status: | Completed |
|---|---|
| Conditions: | Post-Surgical Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 18 - 64 |
| Updated: | 2/3/2019 |
| Start Date: | September 2009 |
| End Date: | June 2010 |
Postoperative Pain After Laparoscopic Cholecystectomy After Anesthesia With Isoflurane, Desflurane, Sevoflurane or Propofol
To the investigators' knowledge, no study has looked at differences in postoperative pain
when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and
propofol in laparoscopic cholecystectomy. The investigators' hypothesis is that total
intravenous anesthesia with propofol will lead to less postoperative pain in the first 24
hours after laparoscopic cholecystectomy when compared to maintenance of anesthesia with
isoflurane, desflurane or sevoflurane.
PURPOSE
To find out if maintenance of anesthesia with propofol leads to less postoperative pain after
laparoscopic cholecystectomy when compared to maintenance of anesthesia with isoflurane,
desflurane, or sevoflurane.
when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and
propofol in laparoscopic cholecystectomy. The investigators' hypothesis is that total
intravenous anesthesia with propofol will lead to less postoperative pain in the first 24
hours after laparoscopic cholecystectomy when compared to maintenance of anesthesia with
isoflurane, desflurane or sevoflurane.
PURPOSE
To find out if maintenance of anesthesia with propofol leads to less postoperative pain after
laparoscopic cholecystectomy when compared to maintenance of anesthesia with isoflurane,
desflurane, or sevoflurane.
Inclusion Criteria:
1. Patient ages 18-64
2. American Society of Anesthesiology Physical Status I, II or III
3. Inpatients scheduled to undergo laparoscopic cholecystectomy at Ben Taub General
Hospital
Exclusion Criteria:
1. Open cholecystectomy - excluded due to increased levels of pain in open procedures
2. Scheduled for ambulatory surgery
3. Renal dysfunction (Serum Cr > 1.2) - excluded due to potential altered metabolism of
anesthetic and pain medications
4. Allergy to any of the study medications or anesthetic agents
5. Chronic opioid analgesic use at home - excluded due to potential difficulty in
assessing pain caused by the procedure alone
6. Patient inability to properly describe postoperative pain to investigators (language
barrier, dementia, delirium, psychiatric disorder)
7. Patient or surgeon refusal
We found this trial at
1
site
Ben Taub General Hospital Located in the heart of the Texas Medical Center, Ben Taub...
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