Use of Epidurals Intraoperatively for Patients Undergoing Pancreas Resection

Status:	Recruiting
Conditions:	Cancer, Cancer, Pancreatic Cancer
Therapuetic Areas:	Oncology
Healthy:	No
Age Range:	18 - Any
Updated:	11/24/2018
Start Date:	January 30, 2018
End Date:	January 2021
Contact:	Florence Grant, MD
Email:	moses-gf@mskcc.org
Phone:	212-639-8829

Randomized Controlled Trial of Epidural-General Anesthesia Versus General Anesthesia for Open Pancreaticoduodenectomy: Influence on Complications and Overall Two Year Survival

The purpose of this study is to see if there is a difference in complications in patients who
have an epidural started earlier (during their surgery) and used as part of the anesthetic in
addition to using it for post operative pain compared with patients who receive an epidural
later in the surgery to be used only for post operative pain.

Inclusion Criteria:

- Adult patients ≥ 18 years of age who can provide informed consent

- Scheduled for pancreaticoduodenectomy

Exclusion Criteria:

- Pregnancy

- History of documented anaphylaxis or contraindication to any of the study medications

- Significant cognitive impairment or documented psychologic impairment

- Contraindication to epidural per Pain Service guidelines

- Use of a sustained release opioid medication such as long-acting morphine, fentanyl
patches, methadone, and buprenorphine within the last 3 months

- Post randomization exclusion will occur if the patient is found to have unresectable
disease at laparotomy and therefore will not have the potential for the same
postoperative complications.

We found this trial at

sites

Memoral Sloan Kettering Basking Ridge (Consent only)

136 Mountainview Boulevard
Basking Ridge, New Jersey 07920

Phone: 212-639-8829

from

Basking Ridge, NJ