A Comparative Study of Subjects Past Their Final Follow-ON Visit

A comparative study to follow subjects who received stem cell therapies three, five, seven,
and nine years after their follow-on visit. Subjects will be selected from a pool of previous
Interdisciplinary Stem Cell Institute trial participants.

Subjects will be followed during the study depending on the initial visit for this trial. The
time point at which they are followed will depend on the subject's injection date in the
previous trial. Depending on the subjects first treatment date (Day of injection) in the
previous Interdisciplinary Stem Cell Institute (ISCI) cardiovascular clinical trial, subjects
may be eligible for one to four study visits in this trial. Those who do not have a three,
five or seven-year visit may receive informed consent at the year nine visit. Thus, subjects
can be enrolled and consented at any visit if the previous eligible visit was missed.

Inclusion Criteria:

- Be 18 years of age and older

- Provide written informed consent

- Have been previously enrolled or currently participating in an investigator-initiated
cardiovascular trial at ISCI (In cases where participants are currently enrolled in
another clinical trial they are still able to participate concurrently in this trial).

Exclusion Criteria:

- Have known, serious radiographic contrast allergy, which cannot be managed with
premedication only if able to undergo MRI or CT.

- Have a history of drug or alcohol abuse within the past 24 months