Endoscopic Mucosal Resection (EMR) in Barrett's Esophagus
| Status: | Enrolling by invitation |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 1/20/2019 |
| Start Date: | October 2007 |
| End Date: | October 2025 |
Endoscopic Mucosal Resection in Barrett's Esophagus
Existing records will be reviewed to evaluate the predictors of complications including
stricture formation, bleeding or perforation associated with endoscopic mucosal resection
stricture formation, bleeding or perforation associated with endoscopic mucosal resection
Barrett's esophagus (BE) is a complication of gastroesophageal reflux disease in which the
normal squamous lining of the esophagus is replaced by specialized columnar epithelium.1
Approximately 5%-10% of patients diagnosed with BE are thought to be at risk of developing
esophageal adenocarcinoma.2 Patients with high-grade dysplasia (HGD) on biopsy are at the
greatest cancer risk³. EMR is being performed clinically in our Barrett's Esophagus Unit on a
regular basis during endoscopy for patients with Barrett's Esophagus and/or early esophageal
adenocarcinoma. There are two predominant endoscopic mucosal resection (EMR) techniques exist
using FDA approved devices - the EMR cap method using a transparent cap/snare combination and
the endoscopic variceal ligation method using a band ligator/snare combination to resect
tissue.
normal squamous lining of the esophagus is replaced by specialized columnar epithelium.1
Approximately 5%-10% of patients diagnosed with BE are thought to be at risk of developing
esophageal adenocarcinoma.2 Patients with high-grade dysplasia (HGD) on biopsy are at the
greatest cancer risk³. EMR is being performed clinically in our Barrett's Esophagus Unit on a
regular basis during endoscopy for patients with Barrett's Esophagus and/or early esophageal
adenocarcinoma. There are two predominant endoscopic mucosal resection (EMR) techniques exist
using FDA approved devices - the EMR cap method using a transparent cap/snare combination and
the endoscopic variceal ligation method using a band ligator/snare combination to resect
tissue.
Inclusion Criteria:
- Barrett's Esophagus Early Esophageal Adenocarcinoma History of Endoscopic Mucosal
Resection
Exclusion Criteria:
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