Effects of Vitamin B12 Treatment in Singers
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 2/21/2018 |
| Start Date: | October 1, 2017 |
| End Date: | July 1, 2021 |
| Contact: | Michael M Johns, MD |
| Email: | michael.johns@med.usc.edu |
| Phone: | (800) 872-2273 |
Vitamin B12 Treatment in Singers - Assessment of Effects Exploratory Pilot Study
In this study, the investigators aim to assess if vitamin B12 treatment demonstrates a
beneficial effect on voice performance. If so, they wish to examine the relationship between
the vitamin B12 treatment and the study participant's general well-being.
beneficial effect on voice performance. If so, they wish to examine the relationship between
the vitamin B12 treatment and the study participant's general well-being.
Through the investigators' experience, they have observed that amongst singers and voice
professionals, there is a common belief that there are voice benefits from cobalamin
treatment. Consequently, some singers and voice professionals tend to ask for cobalamin
injections in order to enhance their vocal performance. However, there are no previous
reports that illustrate the effects of vitamin B12 deficiency or treatment on voice
performance.
professionals, there is a common belief that there are voice benefits from cobalamin
treatment. Consequently, some singers and voice professionals tend to ask for cobalamin
injections in order to enhance their vocal performance. However, there are no previous
reports that illustrate the effects of vitamin B12 deficiency or treatment on voice
performance.
Inclusion Criteria:
- Aged 18 to 65 years old
- An active singer who is presently singing
- Willing and able to comply with the study requirements
- Completed and signed an informed consent form.
Exclusion Criteria:
- Known vitamin B12 deficiency
- Active or recent vitamin B12 treatment (the subject must not receive vitamin B12
treatment for at least 4 weeks)
- Any known bleeding disorder
- Any known laryngeal pathology
- Plans to start any new treatment, oral/parenteral anticoagulant, supplement, or
medication during the study period
- Scored above the highest 10 percentile of performance in all three voice evaluation
questionnaires will be withdrawn from the study before the first injection (i.e.,
scored less than or equal to 7 in the Voice Fatigue Index (VFI), less than or equal to
6 in the Evaluation of the Ability to Sing Easily (EASE), and less than or equal to 4
in the Singing Voice Handicap Index 10 (SVHI-10))
We found this trial at
1
site
830 South Flower Street
Los Angeles, California 90017
Los Angeles, California 90017
Phone: 323-865-9839
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