Promoting Breast Cancer Screening in Women Who Survived Childhood Cancer

The primary purpose of this study is to determine the impact of maximizing patient and
primary care provider (PCP) activation on breast cancer surveillance rates among women
previously treated with chest radiotherapy (RT) for a childhood cancer. This is a 12-month,
3-arm randomized controlled trial using a smartphone intervention with data being collected
at baseline and 12-months through patient and provider surveys and medical record review.
Eligible women treated for a childhood cancer with chest RT will be randomly sampled from the
Childhood Cancer Survivor Study (CCSS) and randomly selected to one of three groups: control,
patient activation (PA) using a smartphone-based intervention, or patient activation +
primary care provider activation (PA+PCP) which will include physician materials about breast
cancer risk in this population along with guidelines for breast cancer surveillance.
Participants in all groups will receive mailed targeted print materials as an educational
resource about their previous chest radiation and breast cancer screening recommendations.
The primary outcome is a medical record confirmed breast MRI and mammogram with the goal of
increasing the rate of women completing the national guideline-based recommended combination
of breast MRI and mammogram. This study will test the hypothesis that women in the PA and
PA+PCP groups will have significantly higher rates of breast cancer surveillance (breast MRI
and mammogram) than women in the control group. In addition, the hypothesis that women in the
PA+PCP group will have significantly higher rates of breast cancer surveillance than women in
the PA group will also be tested.