Molecular Characterization of Neuroblastic Tumor: Correlation With Clinical Outcome



Status:Recruiting
Conditions:Brain Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any
Updated:12/6/2018
Start Date:September 26, 2000
End Date:September 2019
Contact:Nai-Kong Cheung, M.D., Ph.D.
Phone:646-888-2313

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The purpose of this study is to find out the genetic and biochemical makeup of your
neuroblastic tumor, which influences its aggressiveness and the suitable therapy. These
research studies include surface marker analysis, cytogenetics, cancer genes,genome
sequencing, tumor growth-related genes and tumor growth in test tubes. Your blood, marrow,
and hematopoietic stem cell samples will also be tested for tumors or leukemia cells, and
your serum tested for anti-tumor antibodies.

To collect tumor, marrow specimens prospectively to study the molecular-genetic makeup of
individual neuroblastic tumor and its metastasis by blood and marrow, and to correlate these
findings with clinical outcome, and to relate the signaling circuitry of neuroblastic tumors
to that of embryonic neuroectodermal cells. .

Inclusion Criteria:

- Neuroblastic tumors diagnosed in accordance with the International Neuroblastoma
Staging System

OR

- Clinically suspected neuroblastic tumors.

Exclusion Criteria:
We found this trial at
1
site
1275 York Ave
New York, New York 10021
(212) 639-2000
Principal Investigator: Nai-Kong Cheung, M.D., Ph.D.
Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center — the world's oldest and...
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