The Altered Immune Response to Exercise in Patients With Fibromyalgia Before and After a Mind-body Intervention

Inclusion Criteria for FM Patients:

- Patients with a diagnosis of FM

- Clearance from patient's physician to participate in a clinical trial

- Not participating or willing to discontinue FM treatment with trans-cutaneous
electrical nerve stimulation, biofeedback, tender-point injections, acupuncture, Yoga,
and Tai Chi.

Exclusion Criteria for all Participants:

- Diagnosis of severe psychiatric illness

- Abuse of alcohol, benzodiazepines, or other drugs

- Active cardiovascular, pulmonary, hepatic, renal, gastrointestinal, or autoimmune
disease (except Hashimoto's or Graves' disease that has been stable for 3 months
before screening)

- Current systemic infection

- Active cancer (except basal cell carcinoma);

- Unstable endocrine disease

- Severe sleep apnea

- Prostate enlargement or other genitourinary disorder (male patients)

- Pregnancy or breastfeeding

Inclusion Criteria for Healthy Controls:

- Female

- No apparent medical condition that will interfere with participation in the study

- Not on any medication that will interfere with participation in this study

Exclusion Criteria for Healthy Controls:

- Medical or surgical conditions including medication that preclude participation in the
study

- Presence of motor or neuromuscular deficits that may preclude participating in fatigue
exercise