Magnetic Resonance Spectroscopic Imaging of the Prostate at 3 Tesla

Inclusion Criteria:

- Patient must have clinically suspected or biopsy proven prostate cancer. If a patient
has been diagnosed with prostate cancer an official report of biopsy from MSKCC or
outside site is required. All outside pathology reports will be confirmed at MSKCC.

- For those patients who have undergone prostate biopsy it is recommended that the
interval between biopsy and protocol MRI/MRSI should be at least 8 weeks.

- Patient is a potential surgical candidate for treatment of prostate cancer

- Patient is willing to undergo an endorectal MRI/MRSI exam on the 3.0T MR scanner

Exclusion Criteria:

- Patients who because of general medical or psychiatric condition, or physiologic
status unrelated to the presence of prostate cancer cannot give valid informed
consent.

- Patients who are unwilling or unable to undergo MRI/MRSI (including patients with
contra-indications to MRI such as the presence of cardiac pacemakers or non-compatible
intracranial vascular clips.

- Patients who cannot tolerate or have contra-indications to endorectal coil insertion;
for example, patients who have had a prior abdominoperineal resection of the rectum or
have Crohn's disease, patients with severe hemorrhoids, patients who have had prior
radiation to the pelvis to treat a malignancy, or patients who have had minor rectal
surgery within the previous 8 weeks.

- Patients with an allergic reaction to latex.

- Patients with a metallic hip implant or any other metallic implant or device in the
pelvis that might distort local magnetic field and compromise quality of MRI/MRSI.