Using TRAP to Evaluate the Effect of Zometa on Bone Metastasis Due to Lung Cancer



Status:Terminated
Conditions:Lung Cancer, Lung Cancer, Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:4/17/2018
Start Date:February 2005
End Date:December 2010

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Bone Metabolic Markers, TRAP, and Zometa's Effect on Bone Metastasis Due to Lung Cancer

The purpose of this study is to evaluate a new blood test as a way to follow the effect of
Zometa in treating bone metastases due to lung cancer.

The purpose of this research study is to evaluate a new blood test as a way to follow the
effect of Zometa in treating bone metastases. The blood test will look for a protein, called
TRAP, which is released into the blood stream by the breakdown of bone. This study will
compare the TRAP blood test with other blood tests for bone destruction.

Inclusion Criteria:

- invasive lung cancer (small cell or non-small cell lung cancer)

- osteolytic bone metastasis determined by clinical exam, bone scan/XR

- age > 18 years

Exclusion Criteria:

- concurrent malignancy with a second primary

- renal failure (serum creatinine > 3mg/dl)

- pregnancy

- active rheumatoid arthritis

- intolerance to zoledronic acid
We found this trial at
1
site
529 S Jackson St
Louisville, Kentucky 40202
(502) 562-4369
James Graham Brown Cancer Center No one should feel compelled to leave Kentucky to seek...
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