Early Detection of Glioblastoma Multiforme (GBM) Treatment Responses Using Multiple Magnetic Resonance Modalities
| Status: | Completed |
|---|---|
| Conditions: | Brain Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - 80 |
| Updated: | 5/5/2014 |
| Start Date: | November 2006 |
| End Date: | November 2010 |
| Contact: | Jonathan Knisely, MD |
| Email: | jonathan.knisely@yale.edu |
| Phone: | 203-785-6128 |
The purpose of this study is to determine whether dynamic contrast enhanced MRI (DCE MRI)
and high diffusion weighting MRI may be used to distinguish between favorable and
unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be
correlated with histopathologic findings and clinical responses to radiation therapy with or
without chemotherapy.
and high diffusion weighting MRI may be used to distinguish between favorable and
unfavorable responses to therapy of glioblastoma multiforme. Imaging data will be
correlated with histopathologic findings and clinical responses to radiation therapy with or
without chemotherapy.
Inclusion Criteria:
- The presence of a primary brain tumor that cannot be completely resected that
requires radiation therapy with or without chemotherapy.
Exclusion Criteria:
- Patients who do not have a primary brain tumor or who are unable to tolerate the
environment of the MRI scanner
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