Phase II Efficacy Study Looking at a Single-dose of One of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis
Status: | Completed |
---|---|
Conditions: | Psoriasis |
Therapuetic Areas: | Dermatology / Plastic Surgery |
Healthy: | No |
Age Range: | 18 - 65 |
Updated: | 4/17/2018 |
Start Date: | September 10, 2008 |
End Date: | September 17, 2009 |
Phase II Single Dose, Randomized, Double-blind, Multi-center, Parallel-group, Placebo-controlled Study to Assess the Efficacy of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis
This is an exploratory, 4 arm, parallel group, placebo-controlled study comparing three doses
of AIN457 to placebo. Subjects with a diagnosis of moderate to severe chronic plaque
psoriasis will be randomized to receive either AIN457 at one of the three doses studied or
placebo.
of AIN457 to placebo. Subjects with a diagnosis of moderate to severe chronic plaque
psoriasis will be randomized to receive either AIN457 at one of the three doses studied or
placebo.
Inclusion Criteria:
- Diagnosis of plaque psoriasis for at least 6 months prior to screening. The patients
must meet all of the following criterion:
1. Coverage of the body surface area (BSA) of 10% or more with plaques
2. A score of 3 or more on the IGA (Investigator Global Assessment) scale
3. A PASI score of at least 12 at baseline;
Exclusion Criteria:
- Have forms of psoriasis other than the required "plaque psoriasis"
- Women of childbearing potential
- Recent use of investigational drugs or treatment with other biological therapies
(wash-out periods required)
- Previous treatment with this investigational drug
- Subjects with active or history of clinically significant cardiac, kidney or liver
abnormalities
Other protocol-defined inclusion/exclusion criteria may have applied.
We found this trial at
5
sites
Click here to add this to my saved trials

Click here to add this to my saved trials

Click here to add this to my saved trials

Click here to add this to my saved trials

Click here to add this to my saved trials
