Treatment of Comorbid Sleep Disorders and Post Traumatic Stress Disorder (PTSD)
Status: | Active, not recruiting |
---|---|
Conditions: | Insomnia Sleep Studies, Insomnia Sleep Studies, Hospital, Psychiatric, Psychiatric |
Therapuetic Areas: | Psychiatry / Psychology, Other |
Healthy: | No |
Age Range: | 18 - 50 |
Updated: | 9/29/2018 |
Start Date: | August 2016 |
End Date: | September 2020 |
The primary objective of the current study is to determine if providing cognitive-behavioral
therapy of Insomnia and nightmares (CBTin) and Cognitive Processing Therapy of PTSD (CPT)
results in greater PTSD and sleep symptom reduction than CPT only. A secondary objective is
to determine if the sequencing of CBTl&N before or after CPT results in differential effects
on PTSD and sleep symptom reduction.
therapy of Insomnia and nightmares (CBTin) and Cognitive Processing Therapy of PTSD (CPT)
results in greater PTSD and sleep symptom reduction than CPT only. A secondary objective is
to determine if the sequencing of CBTl&N before or after CPT results in differential effects
on PTSD and sleep symptom reduction.
Inclusion Criteria:
- Aged 18-50.
- Chronic Insomnia, as defined by the Diagnostic and Statistical Manual-fifth edition
(DSM-5) (American Psychiatric Association, 2013) assessed with Structured Clinical
Interview for DSM-5 Sleep Disorders (SCISD).
- Chronic Nightmare Disorder, as defined by DSM-5, assessed with the SCISD.
- PTSD, as defined by DSM-5, assessed by Clinician-Administered Posttraumatic Stress
Scale-5 (CAPS-5).
- Active duty military and recently discharged Veterans at Fort Hood eligible for
treatment at Carl R. Darnall Army Medical Center (CRDAMC).
- History of having deployed in support of combat operations following 9/11, assessed by
self-report.
- Stable on psychotropic and/or hypnotic medications and/or interventions for sleep
(e.g., Continuous Positive Air Pressure for sleep apnea) administered by other
providers for at least one month assessed by self-report and review of medical record.
- Willing to refrain from new behavioral health or medication treatment for issues
pertaining to sleep, PTSD, or nightmares during participation in the study.
- Indication that the individual plans to be in the area for the 5 months following the
first assessment.
Exclusion Criteria:
- Individuals who have been re-deployed from a theater of operation less than 3 months.
- Current suicide or homicide risk meriting crisis intervention as assessed by the
Patient Health Questionnaire (PHQ-9), The Depressive Symptom Index - Suicidality
Subscale (DSI-SS), or the Self-Injurious Thoughts and Behaviors Interview (SITBI).
- Inability to speak and read English.
- Moderate to severe brain damage, assessed by the inability to comprehend the baseline
questionnaires.
- Pregnancy, assessed by self-report and review of medical record, because sleep
disturbances due to pregnancy may be the result of different mechanisms and the
proposed instruments and treatments have not been validated in this population.
- Current circadian rhythm, environmental, sleep deprivation, or hypersomnia sleep
disorder, assessed by self-report because CBTin has not been validated in these
populations.
- Other untreated sleep disorders to include individuals with clinically significant
obstructive sleep apnea (Respiratory Disturbance Index >5/hr), periodic limb movement
disorder (PLMD; >15/hr with arousals), nocturnal seizures, or a parasomnia (e.g.,
sleepwalking, confusional arousals, nocturnal eating and drinking syndrome), based on
criteria from the International Classification of Sleep Disorders-third edition
(American Academy of Sleep Medicine, 2013). Individuals meeting criteria for one of
the above sleep disorders will be seen for clinical care at the CRDAMC Sleep Center.
Once the aforementioned sleep disorder is stably treated, individuals meeting the
study criteria for insomnia, nightmares, and PTSD can be reassessed for participation
in this study.
- Sleep efficiency >85%, as assessed by the sleep diary.
- Serious mental health diagnosis (e.g., bipolar disorder or psychosis) assessed with
review of baseline questionnaires, review of medical record, and/or Mini International
Neuropsychiatric Interview (MINI 7.0 Mania module).
- Currently engaged in evidence-based psychotherapy for PTSD (i.e., Prolonged Exposure
Therapy or Cognitive Processing Therapy) or Insomnia or nightmares (i.e., Cognitive
Behavioral Therapy) by self-report and review of medical record.
We found this trial at
1
site
Fort Hood, Texas 76544
Principal Investigator: Karin Nicholson, MD, FACP
Phone: 254-288-1630
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