Ultrasound Assessment of Ventral Hernia Defects
| Status: | Completed |
|---|---|
| Conditions: | Gastrointestinal, Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 20 - 70 |
| Updated: | 4/17/2018 |
| Start Date: | April 2016 |
| End Date: | September 15, 2017 |
Quantitative radiographic imaging holds promise as a novel and innovative strategy to assess
ventral hernia patients. Assessing abdominal wall changes surrounding ventral hernia using
shear wave velocity values measured with ultrasound will identify features of the abdominal
wall that differ between healthy volunteers and subjects scheduled to have ventral hernia
repair. Through the use of ultrasound including shear wave velocity measurements, the
abdominal wall of 25 subjects scheduled to have ventral hernia repair will be compared to
those of 35 healthy volunteers. The ultrasound measurements will elucidate if ventral hernia
affects abdominal wall elasticity and effect surgical outcomes.
ventral hernia patients. Assessing abdominal wall changes surrounding ventral hernia using
shear wave velocity values measured with ultrasound will identify features of the abdominal
wall that differ between healthy volunteers and subjects scheduled to have ventral hernia
repair. Through the use of ultrasound including shear wave velocity measurements, the
abdominal wall of 25 subjects scheduled to have ventral hernia repair will be compared to
those of 35 healthy volunteers. The ultrasound measurements will elucidate if ventral hernia
affects abdominal wall elasticity and effect surgical outcomes.
ARFI-SWV Ultrasound holds promise as an inexpensive, noninvasive, point-of-care diagnostic
tool for pre-operatively predicting successful hernia repair. The investigators propose to
develop and refine a quantitative ultrasound protocol to measure abdominal wall features
suitable for predicting successful closure of the midline fascia. ARFI-SWV ultrasound
represents a novel and intriguing modality for real time visualization and characterization
of changes in the biomechanical properties of diseased musculoskeletal tissues.
In this study, ARFI-SWV ultrasound is hypothesized to preoperatively measure the stiffness in
the lateral abdominal wall as an estimation for mobility during hernia repair. Preoperatively
evaluating hernia severity through ARFI-SWV ultrasound will be performed to identify
mechanical characteristics of the abdominal musculature to predict success of midline fascial
re-approximation in hernia patients. The study proposes to compare ultrasound images and
associated shear wave velocity measurements between 35 healthy volunteers and 25 subjects
undergoing surgical repair for ventral hernia. Subjects with ventral hernia will undergo
imaging no earlier than two weeks prior to elective hernia repair and again postoperatively
within six months following repair at a standard followup visit. Statistical analysis will
determine if there is a significant difference in the abdominal wall stiffness, represented
by the ultrasound shear wave velocity measurements, between the healthy subjects and the
subjects with ventral hernia. Further analysis will determine if there is any statistically
significant relationship between abdominal wall stiffness of subjects with ventral hernia and
surgical outcomes.
tool for pre-operatively predicting successful hernia repair. The investigators propose to
develop and refine a quantitative ultrasound protocol to measure abdominal wall features
suitable for predicting successful closure of the midline fascia. ARFI-SWV ultrasound
represents a novel and intriguing modality for real time visualization and characterization
of changes in the biomechanical properties of diseased musculoskeletal tissues.
In this study, ARFI-SWV ultrasound is hypothesized to preoperatively measure the stiffness in
the lateral abdominal wall as an estimation for mobility during hernia repair. Preoperatively
evaluating hernia severity through ARFI-SWV ultrasound will be performed to identify
mechanical characteristics of the abdominal musculature to predict success of midline fascial
re-approximation in hernia patients. The study proposes to compare ultrasound images and
associated shear wave velocity measurements between 35 healthy volunteers and 25 subjects
undergoing surgical repair for ventral hernia. Subjects with ventral hernia will undergo
imaging no earlier than two weeks prior to elective hernia repair and again postoperatively
within six months following repair at a standard followup visit. Statistical analysis will
determine if there is a significant difference in the abdominal wall stiffness, represented
by the ultrasound shear wave velocity measurements, between the healthy subjects and the
subjects with ventral hernia. Further analysis will determine if there is any statistically
significant relationship between abdominal wall stiffness of subjects with ventral hernia and
surgical outcomes.
Inclusion Criteria:
- male or female between 20-70 years of age
- healthy volunteer or seeking elective ventral hernia repair
Exclusion Criteria:
- pregnant women
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