Support for Perinatal Adherence and Depression



Status:Active, not recruiting
Conditions:Depression, Depression, HIV / AIDS, HIV / AIDS, HIV / AIDS
Therapuetic Areas:Immunology / Infectious Diseases, Psychiatry / Psychology
Healthy:No
Age Range:18 - 45
Updated:4/17/2018
Start Date:September 7, 2016
End Date:December 2018

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Project INSPireD: Integrating Nuanced Support for Perinatal Adherence and Depression

The main aim is to conduct a pilot field test of a group-based depression and adherence
counseling intervention with HIV-infected women in the perinatal period. Participants will be
HIV-infected women living in KwaZulu-Natal, South Africa.

The main aim of this study is to conduct a pilot field test of a group-based counseling
intervention with HIV-infected women in the perinatal period as delivered by a lay counselor.
The primary goal of the intervention is to reduce symptoms of perinatal depression and
increase adherence to antiretroviral therapy among HIV-infected women during pregnancy and
the postpartum period.

Inclusion Criteria:

- Currently pregnant

- HIV-infected and diagnosed with HIV during the index pregnancy

- Meet criteria for a major depressive episode

- Currently on antiretroviral therapy

- Receiving antenatal care at PMMH Gateway clinic

- Primary language English or isiZulu

- Access to a phone and willing to give researchers permission to reach them via phone

- Resident of Umlazi

Exclusion Criteria:

- Unable or unwilling to provide informed consent

- Active untreated, major mental illness (untreated psychosis, bipolar disorder,
dementia, or active suicidality) that would interfere with study participation

- Less than 18 years of age
We found this trial at
2
sites
Durban,
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Durban,
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185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
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Boston, MA
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