Ceftriaxone and Jaundice in Neonates
| Status: | Recruiting |
|---|---|
| Healthy: | No |
| Age Range: | Any |
| Updated: | 4/17/2018 |
| Start Date: | March 2016 |
| End Date: | December 31, 2018 |
Effect of Ceftriaxone on Neonatal Jaundice
Ceftriaxone is an antibiotic often used for the management of sepsis. Neonates commonly have
jaundice during the first postnatal week. The effect of ceftriaxone on jaundice has not been
investigated in well designed studies
jaundice during the first postnatal week. The effect of ceftriaxone on jaundice has not been
investigated in well designed studies
The ceftriaxone may affect jaundice concentration specifically binding of bilirubin to
albumin. The study will evaluate the effect of ceftriaxone on bilirubin binding in neonates
with a diagnosis of sepsis.
albumin. The study will evaluate the effect of ceftriaxone on bilirubin binding in neonates
with a diagnosis of sepsis.
Inclusion Criteria:
- infants with sepsis requiring IV antibiotics for more than 3 days and who has total
serum bilirubin < 12 mg/dL but otherwise stable and healthy to be discharged home
Exclusion Criteria:
- Infants with asphyxia, chromosomal disorder, hearing loss, moderate to severe
jaundice, unstable clinical conditions, respiratory distress, cardiac disorders, and
any clinical conditions which will preclude discharge to home.
We found this trial at
1
site
601 Elmwood Avenue
Rochester, New York 14642
Rochester, New York 14642
(585) 275-2100
Phone: 585-273-2696
Univ of Rochester Medical Center One of the nation's top academic medical centers, the University...
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