Suprachoroidal Injection of Triamcinolone Acetonide With IVT Anti-VEGF in Subjects With Macular Edema Following RVO
Status: | Terminated |
---|---|
Conditions: | Cardiology, Ocular, Ocular |
Therapuetic Areas: | Cardiology / Vascular Diseases, Ophthalmology |
Healthy: | No |
Age Range: | 18 - Any |
Updated: | 1/11/2019 |
Start Date: | March 5, 2018 |
End Date: | December 18, 2018 |
A RANDOMIZED, MASKED, CONTROLLED TRIAL TO STUDY THE SAFETY AND EFFICACY OF SUPRACHOROIDAL CLS-TA IN COMBINATION WITH AN INTRAVITREAL ANTI-VEGF AGENT IN SUBJECTS WITH RETINAL VEIN OCCLUSION
This Phase 3, multicenter, randomized, masked, controlled, parallel group study is designed
to demonstrate that suprachoroidal (SC) CLS-TA administered with intravitreal (IVT) anti-VEGF
agent in subjects with treatment naive RVO is superior to IVT anti-VEGF agent used alone.
to demonstrate that suprachoroidal (SC) CLS-TA administered with intravitreal (IVT) anti-VEGF
agent in subjects with treatment naive RVO is superior to IVT anti-VEGF agent used alone.
A Randomized, Masked, Controlled Trial to Study the Safety and Efficacy of Suprachoroidal
CLS-TA With Intravitreal Anti-VEGF Agent in Subjects With Retinal Vein Occlusion
CLS-TA With Intravitreal Anti-VEGF Agent in Subjects With Retinal Vein Occlusion
Inclusion Criteria:
- Has a clinical diagnosis of RVO in the study eye
- Has a CST of ≥ 300 µm in the study eye
- Has an ETDRS BCVA score of ≥ 20 letters read and ≤ 70 letters read in the study eye
- Is naïve to local pharmacologic treatment for RVO in the study eye
Exclusion Criteria:
- Any active ocular disease or infection in the study eye other than RVO
- History of glaucoma, intraocular pressure > 21 mmHg or ocular hypertension requiring
more than one medication
- Any uncontrolled systemic disease that, in the opinion of the Investigator, would
preclude participation in the study
- Any evidence of neovascularization in the study eye
We found this trial at
73
sites
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