Dynamic Magnetic Resonance Imaging Before and After Vaginal Prolapse Repair

Approximately 1 in 11 women will undergo surgery for POP by age 80 years. POP occurs due to a
defect or weakness of the pelvic floor, resulting in the herniation of pelvic organs through
the vagina. The goal of surgical interventions has historically been thought to restore
normal pelvic anatomy. Restoration of pelvic anatomy has been demonstrated following pelvic
reconstructive surgery by way of significantly improved postoperative Pelvic Organ Prolapse
Quantification (POPQ) scale measurements. Furthermore, improved POPQ measurements have also
been shown to be positively correlated with improved patient satisfaction.

More recently, attention has turned toward using imaging studies to describe the
postoperative anatomical changes seen in pelvic reconstructive surgery. The purpose of this
study is to describe the impact of vaginal reconstruction, including an intraperitoneal
vaginal vault suspension for POP on pelvic anatomy using dynamic MRI of the pelvis.

The primary aim is to compare postoperative dynamic pelvic MRI measurements to preoperative
measurements in patients who undergo prolapse repair vaginally including anterior, posterior
and intraperitoneal vaginal vault suspension repairs for POP.

Inclusion Criteria:

- Adults 18 years of age or older

- English-speaking

- Undergoing anterior, posterior and intraperitoneal vaginal vault suspension by a
physician at Cincinnati Urogynecology Associates, TriHealth for the treatment of
symptomatic POP

- Concomitant procedures such as hysterectomy, suburethral sling, bilateral
salpingectomy or salpingooophorectomy

- Willingness to participate in study

Exclusion Criteria:

- Unwillingness to participate in the study

- Pregnancy

- Contraindication to pelvic MRI, such as a metal implanted device (excluding titanium)
or claustrophobia

- Previous surgery for apical prolapse such as sacrocolpopexy or vaginal vault
suspension, or transvaginal mesh for prolapse

- Physical or mental impairment that would affect the subject's ability to complete the
dynamic MRI, including patient's with dementia or those who have impaired mobility

- Known findings that may distort pelvic anatomy, such as a pelvic mass, congenital
anomaly, or history of pelvic radiation