Exploratory Study of Volatile Organic Compounds in Alveolar Breath



Status:Active, not recruiting
Conditions:Food Studies, Endocrine
Therapuetic Areas:Endocrinology, Pharmacology / Toxicology
Healthy:No
Age Range:18 - Any
Updated:3/15/2019
Start Date:October 1, 2011
End Date:December 1, 2019

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Retrospective Analysis of Volatile Organic Compounds in Alveolar Breath as Biomarkers of Idiopathic Malodor

The purpose of this secondary analysis is to identify breath signatures associated with
idiopathic malodor conditions.

Individuals with metabolic disorders may sporadically produce malodors despite good hygiene.
Analysis of volatile organic compounds (VOCs) helps to gain insights into medical conditions
arising due to metabolic dysfunction as different metabolic pathways emit and or consume
various VOCs. These VOCs can be detected via the exhaled breath collected and analyzed with a
portable breath collection apparatus. VOC profiles will be compared with self-reported
symptoms and other observations of participating subjects.

Inclusion Criteria:

- good general health

- willing and able to travel to one of the participating sites

Exclusion Criteria:

- medical conditions that, in the opinion of the investigator, would prevent
participation

- elect not to participate in the study
We found this trial at
2
sites
Miami, Florida 33175
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Miami, FL
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London, England
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London,
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