Characterization and Prediction of Atrial Fibrillation-caused Adverse Events After Hospital Discharge for Cardiac Surgery
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Atrial Fibrillation, Neurology |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Neurology |
| Healthy: | No |
| Age Range: | 20 - Any |
| Updated: | 12/13/2018 |
| Start Date: | January 1, 2018 |
| End Date: | December 31, 2019 |
Massachusetts-wide Study of the Incidence of ATrial Fibrillation and Stroke Occurring After Discharge From Cardiac Surgery (MATRICeS)
The purpose of the research is to identify the frequency and severity of adverse events
related to atrial fibrillation that occur after discharge from hospital where the patient
underwent cardiac surgery.
The Specific Aims of the proposed study are to:
1. Identify the predictors of postoperative atrial fibrillation after discharge from
hospital.
2. Identify the frequency of readmission to hospital, or other resource use such as
Emergency Department or outpatient visit, for the treatment or prophylaxis of
postoperative AF and consequent stroke or bleeding outcomes.
3. Identify the risks for stroke, death and other morbidity in patients after cardiac
surgery and the effect of postoperative AF upon subsequent stroke or bleeding outcomes.
related to atrial fibrillation that occur after discharge from hospital where the patient
underwent cardiac surgery.
The Specific Aims of the proposed study are to:
1. Identify the predictors of postoperative atrial fibrillation after discharge from
hospital.
2. Identify the frequency of readmission to hospital, or other resource use such as
Emergency Department or outpatient visit, for the treatment or prophylaxis of
postoperative AF and consequent stroke or bleeding outcomes.
3. Identify the risks for stroke, death and other morbidity in patients after cardiac
surgery and the effect of postoperative AF upon subsequent stroke or bleeding outcomes.
Inclusion Criteria:
- Patients who underwent cardiac surgery in Massachusetts between 2012 - 2016
Exclusion Criteria:
- surgical procedures that do not include coronary artery bypass graft surgery, aortic
valve surgery or mitral valve surgery;
- surgical procedures that include MAZE surgery, or pulmonary vein isolation,
ventricular assist device, heart transplantation, congenital heart surgery, bacterial
endocarditis, cardiac trauma, cardiac tumor, ventricular septal defect repair, left
ventricular aneurysm repair, pulmonary thromboendarterectomy, sub-aortic stenosis
resection or surgical ventricular restoration;
- surgical procedures on patients that have undergone MAZE surgery, AF ablation
procedures, pulmonary vein isolation or left atrial appendage resection or ablation
(such as Watchman devices).
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