The Effect of Fontan Fenestration Closure on Hepatic Stiffness
| Status: | Recruiting |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 6/1/2018 |
| Start Date: | May 29, 2018 |
| End Date: | June 30, 2020 |
| Contact: | Rahul Rathod, MD |
| Email: | rahul.rathod@childrens.harvard.edu |
| Phone: | 617-355-4890 |
The overarching goal of this project is to discern how closure of Fontan fenestrations in
patients with single ventricle heart disease will affect hepatic congestion, a major
determinant of chronic liver disease. We will employ transient elastography (Fibroscan) to
obtain liver stiffness measurements (LSM) before and after fenestration closure to study the
impact of this intervention on hepatic congestion.
patients with single ventricle heart disease will affect hepatic congestion, a major
determinant of chronic liver disease. We will employ transient elastography (Fibroscan) to
obtain liver stiffness measurements (LSM) before and after fenestration closure to study the
impact of this intervention on hepatic congestion.
Inclusion Criteria:
- Functional Single ventricle patients after a fenestrated lateral tunnel or
extra-cardiac Fontan
- Patients scheduled for possible fenestration closure in the catheterization laboratory
- Informed consent has been obtained
Exclusion Criteria:
- Patients with spontaneous closure of Fenestration
- Ascites
- Ventilatory requirement
- Implantable cardiac device
- Ongoing inotropic support
- Pregnancy
- Inability to tolerate four hour pre-procedure fasting
We found this trial at
1
site
300 Longwood Ave
Boston, Massachusetts 02115
Boston, Massachusetts 02115
(617) 355-6000
Phone: 617-355-4890
Boston Children's Hospital Boston Children's Hospital is a 395-bed comprehensive center for pediatric health care....
Click here to add this to my saved trials
