Stroke Motor Rehabilitation and Recovery Study

Participants will be enrolled in the SMaHRT study during their acute stroke hospitalization
and will have research visits spanning the post-stroke care continuum at 6 weeks, 3 months, 6
months, and one year. These research visits will accompany comprehensive clinical visits to
the Stroke Motor Recovery Clinic of the Center for Neurotechnology and Neurorecovery (CNTR,
cntr.mgh.harvard.edu). The study will collect clinical outcome measures, video and
robot-kinematic data, smartphone usage patterns, and EEG data in order to quantify the course
of motor recovery. The goal is to rigorously understand the behavioral, neuroanatomic, and
neurophysiologic underpinnings of motor recovery toward developing personalized strategies
and neurotechnologies to facilitate neurorehabilitation and enable better recovery for people
with stroke.

Inclusion Criteria

- Age 18 - 90

- Upper extremity motor weakness after ischemic stroke

- Ability to follow simple commands in English

- Score of zero or 1 on the NIH Stroke Scale Level of Consciousness Questions 1a and 1b
and a score of zero on the NIH Stroke Scale Level of Consciousness Question 1c.

- Stable medical status as determined by primary care team

- Inpatient on the MGH stroke neurology service

Exclusion Criteria

- Prior history of developmental, neurologic, or major psychiatric disorder resulting in
functional disability

- Prior history of visual or auditory disorders limiting ability to participate in
testing

- Evidence of an uncontrolled seizure disorder

- Patients for whom EEG leads are contraindicated