Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography
| Status: | Terminated |
|---|---|
| Conditions: | High Blood Pressure (Hypertension), Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 10/17/2018 |
| Start Date: | March 23, 2018 |
| End Date: | April 4, 2018 |
A Prospective, Double-blind, Randomized, Placebo-controlled Trial of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography
The overall goal of this study is to detect preclinical signs of HAPE by lung ultrasonography
and evaluate the effectiveness of acetazolamide at decreasing pulmonary edema by using
ultrasound.
and evaluate the effectiveness of acetazolamide at decreasing pulmonary edema by using
ultrasound.
Inclusion Criteria:
1. At least 18 years of age
2. Able to consent
3. English speaking
4. Trekking directly to Everest Base Camp
Exclusion Criteria:
1. Age less than 18 years
2. Non-English speaking
3. Pregnant
4. Already had a diagnosis of acute mountain sickness, high-altitude cerebral edema, or
high-altitude pulmonary edema
5. Been on a high-altitude trek 2 weeks prior to this study
6. Has taken acetazolamide 1 week prior to start of trek
7. Has a sulfa allergy
8. Has any type of acute or chronic pulmonary conditions
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