Emission Patterns of Respiratory Pathogens



Status:Not yet recruiting
Healthy:No
Age Range:18 - Any
Updated:10/31/2018
Start Date:July 2019
End Date:June 2021
Contact:Werner Bischoff, MD
Email:wbischof@wakehealth.edu
Phone:336-716-5116

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Airborne transmission represents one of the most rapidly spreading and dangerous
dissemination mechanisms for pathogens. Public health strategies to prevent and control the
often explosive outbreaks associated with such pathogens are: 1) vaccination and treatment,
if available, 2) isolation and barrier precautions such as face masks, and 3) decontamination
of the exposed areas and surfaces. A lack of understanding how these pathogens are
transmitted hampers the ability to develop effective prevention measures. This study will be
used to collect preliminary data of the emission patterns of respiratory pathogens.

Airborne transmission represents one of the most rapidly spreading and dangerous
dissemination mechanisms for pathogens. The study team have been investigating bacterial and
viral transmission routes and barrier precautions. In a recent clinical study, it was
observed that Measles virus RNA was detected from a patient for at least up to 10 feet. In
addition, the group has been studying barrier precautions (facemasks) for their ability to
prevent the spread of aerosolized viruses. Finally, in a controlled lab setting the
investigators have assessed the impact of environmental conditions (temperature, humidity) on
pathogen transmission and the effect of UV-C light to prevent the spread of influenza. The
purpose of this observational study is to describe the human aerosolization patterns of
respiratory pathogens. The study team hypothesizes that the emission patterns of specific
airborne pathogens varies between individual patients.

Inclusion Criteria:

- patients >18 years of age admitted to the ED or an inpatient care unit of Wake Forest
Baptist Medical Center (WFBMC)

- Positive

Exclusion Criteria:

- positive respiratory pathogen tests
We found this trial at
1
site
Winston-Salem, North Carolina 27157
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from
Winston-Salem, NC
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