Cortical Priming to Optimize Gait Rehabilitation Post Stroke



Status:Recruiting
Conditions:Neurology
Therapuetic Areas:Neurology
Healthy:No
Age Range:40 - 80
Updated:4/17/2018
Start Date:January 1, 2014
End Date:July 31, 2019
Contact:Sangeetha Madhavan, PT, PhD
Email:smadhava@uic.edu
Phone:3123552517

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Over four million stroke survivors currently living in the United States are unable to walk
independently in the community. To increase the effectiveness of gait rehabilitation, it is
critical to develop therapies that are based on an understanding of brain adaptations that
occur after stroke. This project will be the first step towards the development of a novel
therapeutic approach using brain stimulation to increase walking capacity in stroke survivors
and understand the neural mechanisms that are associated with impairment and functional
recovery.


Inclusion Criteria:

- Age 50 - 80 years

- First ever monohemispheric stroke > 6 months since onset

- Residual hemiparetic gait deficits

- Able to walk without an ankle orthotic for 5 minutes at self-paced speed. Handheld
assistive device is acceptable.

Exclusion Criteria:

- Severe osteoporosis

- Contracture-limiting range of motion of lower limb

- Uncontrolled anti-spasticity medications during the study period

- Cardiorespiratory or metabolic diseases (e.g. cardiac arrhythmia, uncontrolled
hypertension or diabetes, chronic emphysema)

- Unhealed decubiti, persistent infection

- Significant cognitive or communication impairment (MMSE <21), which could impede the
understanding of the purpose of procedures of the study or prevent the patient from
performing the tracking task.

- Lesions pertaining to the brainstem and cerebellum
We found this trial at
1
site
2035 W Taylor St
Chicago, Illinois
(312) 996-4350
Phone: 312-355-2517
University of Illinois at Chicago A major research university in the heart of one of...
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