Preoperative Oral Carbohydrate Drink for Elective Cesarean Delivery and the Effect on Insulin Sensitivity



Status:Enrolling by invitation
Conditions:Neurology, Endocrine
Therapuetic Areas:Endocrinology, Neurology
Healthy:No
Age Range:Any - 50
Updated:2/23/2019
Start Date:February 25, 2019
End Date:April 20, 2020

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria
Preoperative fasting and surgery can cause metabolic stress and insulin resistance. Oral
carbohydrate loading has been shown to attenuate the development of insulin resistance in the
non-pregnant population undergoing many different types of surgery. Pregnant women have an
increase in insulin resistance and therefore may further benefit from a preoperative
carbohydrate load prior to cesarean delivery. Although woman in the UK receive a carbohydrate
drink prior to elective cesarean delivery, the metabolic effects of these drinks on the
mother and neonate have not been evaluated.


Inclusion:

- ASA physical status II-III women presenting for scheduled, elective cesarean delivery
under neuraxial anesthesia

- Singleton gestation at term (37-42 weeks)

- Ages 18-50

Exclusion:

- Preexisting diabetes (Gestational diabetes, Type I DM, Type II DM)

- Taking insulin-sensitizing or other medications known to influence glucose or fatty
acid metabolism.

- Kidney, heart, or liver disease. Severe lipid disorders.

- History of bariatric surgery

- Pre-pregnancy BMI >40

- Prolonged period of time (>4 hours) between ingestion of carbohydrate drink and
surgery

- Four or more repeat cesarean sections
We found this trial at
1
site
Mayo Clinic Rochester
200 First Street SW
Rochester, Minnesota 55905
507-284-2511
Mayo Clinic Rochester Mayo Clinic is a nonprofit worldwide leader in medical care, research and...
?
mi
from
Rochester, MN
Click here to add this to my saved trials