IMpact of PRehabilitation in Oncology Via Exercise - Breast Cancer
| Status: | Recruiting |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 3/24/2019 |
| Start Date: | October 15, 2017 |
| End Date: | June 15, 2019 |
| Contact: | Joachim Wiskemann, PhD |
| Email: | jwiskema@phs.psu.edu |
| Phone: | 717-5310003 |
The purpose of this study is to determine whether patients are able to participate in a so
called prehabilitation program (prior to the beginning of cancer treatment) which includes
(1) a supervised and home-based exercise program plus one educational session or (2) just
home-based exercise plus one educational session or (3) just one educational session.
Breast cancer surgery may have potential for several side effects, including functional (e.g.
flexibility in the affected arm, lymphedema [swelling that generally occurs in the arms or
legs that occurs as a result of the removal of or damage to lymph nodes as a part of cancer
treatment], shoulder pain) and psychosocial (e.g. reduced quality of life, increased fatigue)
aspects.
Evidence shows that exercise is considered to be an effective treatment approach in breast
cancer patients during and after treatment with regard to the above mentioned side-effects.
Also, prehabilitative exercise in colon and lung cancer patients was shown as feasible and
effective. However, no experience exits with regard to prehabilitation exercise in breast
cancer patients.
called prehabilitation program (prior to the beginning of cancer treatment) which includes
(1) a supervised and home-based exercise program plus one educational session or (2) just
home-based exercise plus one educational session or (3) just one educational session.
Breast cancer surgery may have potential for several side effects, including functional (e.g.
flexibility in the affected arm, lymphedema [swelling that generally occurs in the arms or
legs that occurs as a result of the removal of or damage to lymph nodes as a part of cancer
treatment], shoulder pain) and psychosocial (e.g. reduced quality of life, increased fatigue)
aspects.
Evidence shows that exercise is considered to be an effective treatment approach in breast
cancer patients during and after treatment with regard to the above mentioned side-effects.
Also, prehabilitative exercise in colon and lung cancer patients was shown as feasible and
effective. However, no experience exits with regard to prehabilitation exercise in breast
cancer patients.
Inclusion Criteria:
- Unilateral or bilateral primary carcinoma of the breast, confirmed histologically by
core biopsy
- Not metastatic (stage <4)
- Females and males ≥18 years of age
- Fluent in written and spoken English
- Must be able to provide and understand informed consent
- Must have an ECOG PS of ≤ 2
- Scheduled for lump- or mastectomy at Penn State Cancer Institute
- ≥ 2 weeks till primary treatment
- Primary attending surgeon approval
Exclusion Criteria:
- Receiving neoadjuvant chemotherapy, radiotherapy or hormone therapy
- Not fluent in written and spoken English
- Evidence in the medical record of an absolute contraindication (e.g. Heart
insufficiency > NYHA III or uncertain arrhythmia; uncontrolled hypertension; severe
renal dysfunction (GFR < 30%, Creatinine> 3mg/dl; insufficient hematological capacity
like either hemoglobin value below 8 g/dl or thrombocytes below 30.000/µL; reduced
standing or walking ability) for exercise
- Pregnant women
- Engaging in systematic intense exercise training (at least 1h twice per week)
We found this trial at
1
site
Click here to add this to my saved trials
