TAP Block Catheters vs Liposomal Bupivacaine for Pain Control After Colorectal Surgery



Status:Recruiting
Conditions:Colorectal Cancer
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - 90
Updated:2/7/2019
Start Date:March 1, 2017
End Date:December 16, 2019
Contact:Jon Zhou, MD
Email:jonzhou@ucdavis.edu
Phone:916-734-5028

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Transversus Abdominus Plane (TAP) Block Catheters vs Liposomal Bupivacaine for Pain Control After Colorectal Surgery: A Prospective Randomized Control Trial

This is a prospective randomized study designed to compare the pain control from a single
shot of liposomal bupivacaine (Exparel) against transversus abominus plane (TAP) catheters
with ropivicaine bolus in patients undergoing elective colorectal surgery.

At UC Davis, it is standard practice to place TAP blocks with catheters for adult colorectal
surgery patients for perioperative pain control. This practice, however, is resource
intensive, adds the risk of catheter-related complications, and adds increased burden to
patients by requiring them to be tethered to 2 catheters.

An alternative TAP can be performed using a single shot of liposomal bupivacaine (Exparel),
an extended release local anesthetic that is FDA-approved for surgical plane infiltration
including TAP blocks.

With this prospective study, we seek to improve patient care at UC Davis and educate other
institutions through the use of concrete data comparing these 2 treatment options.

Inclusion Criteria:

- Patients scheduled for elective colorectal surgery with Dr. Linda Farkas

Exclusion Criteria:

- Patients under 18 years of age

- Patient over 90 years of age

- Pregnancy

- Prisoners

- Patients unable to provide consent

- Patients on systemic anticoagulation therapy

- Patients with an allergy to local anesthetics
We found this trial at
1
site
2315 Stockton Blvd
Sacramento, California 95817
Phone: 916-734-5028
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Sacramento, CA
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