Peripherally Inserted Central Catheter (PICC) Thrombosis: Reverse Taper Versus Non-tapered Catheters
| Status: | Completed |
|---|---|
| Conditions: | Cardiology, Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 90 |
| Updated: | 4/29/2018 |
| Start Date: | August 2008 |
| End Date: | August 2011 |
The purpose of this study is to compare two different marketed PICC (peripherally inserted
central catheter) designs. Clotting rates, procedural bleeding and ease of catheter insertion
will be compared. It is hypothesized that the non-tapered design has a lower clotting rate
and is easier to place than the tapered design. Bleeding rates are expected to be about the
same.
central catheter) designs. Clotting rates, procedural bleeding and ease of catheter insertion
will be compared. It is hypothesized that the non-tapered design has a lower clotting rate
and is easier to place than the tapered design. Bleeding rates are expected to be about the
same.
Inclusion Criteria:
- All inpatients, age 18 to 90, in need of de novo central venous access with a double
lumen catheter indication of > 2 weeks
- Informed consent and HIPAA consent forms discussed and signed by patient or their
authorized representative
Exclusion Criteria:
- Skin related problems around the insertion site (infection, phlebitis, scars)
- History of mastectomy/axillary dissection on insertion side
- Coagulopathy with an INR of > 2.0
- Thrombocytopenia with platelets < 25,000 uL
- Renal insufficiency with a creatinine of > 3.0 mg/dL
- Documented current upper extremity or central venous thrombosis
- Hypercoagulable states (protein C or S deficiency, AT-III deficiency, lupus
anticoagulant)
- Catheters needed for therapy within less than an hour (emergent placement not allowing
sufficient time for proper research consent and randomization)
- Patient has already been enrolled in this research study
- Life expectancy less than 1 month
We found this trial at
1
site
3400 Spruce St
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
(215) 662-4000
Hospital of the University of Pennsylvania The Hospital of the University of Pennsylvania (HUP) is...
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