Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 11/29/2018 |
| Start Date: | November 1, 2006 |
| End Date: | December 1, 2020 |
This research study is being done because patients with a history of chest radiation
treatment for Hodgkin's disease have been shown to be at increased risk for developing lung
cancer a number of years out from treatment. The risk appears to be further increased among
patients with a smoking history. Currently, the practice is to recommend annual low-dose
chest CT scans in survivors of Hodgkin's disease who have received prior chest radiation
treatment and who have at least a moderate smoking history. In this study, the CT scans will
be read and interpreted by the study radiologist, and the results recorded in a consistent
manner.
treatment for Hodgkin's disease have been shown to be at increased risk for developing lung
cancer a number of years out from treatment. The risk appears to be further increased among
patients with a smoking history. Currently, the practice is to recommend annual low-dose
chest CT scans in survivors of Hodgkin's disease who have received prior chest radiation
treatment and who have at least a moderate smoking history. In this study, the CT scans will
be read and interpreted by the study radiologist, and the results recorded in a consistent
manner.
- Participants will undergo a chest computed tomography (CT) scan once a year for a 3-year
period.
period.
Inclusion Criteria:
- 5 years or longer from initial Hodgkin's disease diagnosis
- Current age 18 or older
- Received mediastinal irradiation and/or alkylating-agent based chemotherapy
- Smoking history of 10-pack years or more, or current smoker
- Pre-approval from the participant's insurance company for the CT study
Exclusion Criteria:
- Patients with a history of lung cancer
- Currently receiving treatment for another cancer diagnosis
- Known diagnosis of any metastatic cancer
- Pregnant women
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Brigham and Women's Hosp Boston’s Brigham and Women’s Hospital (BWH) is an international leader in...
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Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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