The Impact of Physical (In)Activity on Sleep Quality



Status:Recruiting
Conditions:Insomnia Sleep Studies
Therapuetic Areas:Psychiatry / Psychology
Healthy:No
Age Range:18 - 35
Updated:5/5/2018
Start Date:April 20, 2018
End Date:December 1, 2019
Contact:Ryan Garten, PhD
Email:rsgarten@vcu.edu
Phone:(804) 828-1948

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The proposed research will examine the role of physical activity (PA) on altering sleep
quality (SQ) while systematically examining novel mechanisms that may drive changes in SQ.
Specifically, the study will examine how a 2 week reduction in PA alters sleep quality in
young, healthy individuals. Additionally, during this reduction in PA, the study will examine
changes in inflammation, oxidative stress, and sympathetic activity to identify potential
mechanisms for alterations in sleep quality.

Sleep, which makes up approximately one third of an individual's life, plays a vital role in
normal bodily functioning by regulating metabolic and endocrine function. Disturbed sleep,
defined as any alteration to normal sleep patterns, is highly prevalent, affecting 35% and
41% of the general population in the United States and has been linked to poor cardiovascular
health, diabetes, obesity, dyslipidemia, and hypertension. Young adults are a population at
high risk for disturbed sleep-related health outcomes due to negative lifestyle behaviors
such as alcohol consumption, drug use, study patterns, and excessive screen time that remain
with advancing age. Due to the importance of improving or maintaining health outcomes through
adequate sleep quality (SQ), the proposed research will examine the role of physical activity
(PA) on altering SQ while systematically examining novel mechanisms that may drive changes in
SQ. Specifically, this study will examine how alterations (increases and decreases) in PA
impact SQ and how these alterations modify inflammation, oxidative stress, and sympathetic
stimulation in young adults.

Inclusion Criteria:

- Healthy individuals with average weekly step count greater than 7500

- Low risk of cardiovascular, pulmonary, and metabolic disease

Exclusion Criteria:

- Individuals with cardiovascular, pulmonary, and metabolic disease

- Individuals taking medications that may affect cardiovascular, pulmonary, and
metabolic function

- Diet differs substantially from typical diet, significant calorie restriction, or
vitamin/mineral deficiencies

- Pregnant women

- Prisoners
We found this trial at
1
site
Richmond, Virginia 23298
(804) 828-0100
Principal Investigator: Ryan Garten, PhD
Virginia Commonwealth University Since our founding as a medical school in 1838, Virginia Commonwealth University...
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Richmond, VA
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