Fructooligosaccharide and Calcium Absorption in Adolescent Girls
| Status: | Completed |
|---|---|
| Conditions: | Osteoporosis |
| Therapuetic Areas: | Rheumatology |
| Healthy: | No |
| Age Range: | 10 - 12 |
| Updated: | 5/9/2018 |
| Start Date: | January 2009 |
| End Date: | June 2009 |
Fructooligosaccharides (FOS) are believed to have positive effects on calcium absorption and
bone accrual during growth. This study aims to see whether the addition of fiber in the form
of FOS to a calcium-containing beverage will increase calcium absorption. During two clinical
visits, participants will receive a beverage containing a small amount of calcium,
supplemented with either no dietary fiber or a small amount of fiber. Height, weight, bone
density and geometry, calcium absorption, and physical fitness will be measured. The effects
of this fiber intervention may provide support for improving bone health with minimal fiber
supplementation.
bone accrual during growth. This study aims to see whether the addition of fiber in the form
of FOS to a calcium-containing beverage will increase calcium absorption. During two clinical
visits, participants will receive a beverage containing a small amount of calcium,
supplemented with either no dietary fiber or a small amount of fiber. Height, weight, bone
density and geometry, calcium absorption, and physical fitness will be measured. The effects
of this fiber intervention may provide support for improving bone health with minimal fiber
supplementation.
Inclusion Criteria:
- Female
- Calcium intake of 900-1300 mg/d
- Generally healthy
Exclusion Criteria:
- Male
- BMI > 90th percentile for age
- Takes medication that influences calcium metabolism
- Any disorder of calcium or bone homeostasis (hypercalcemia, Paget's Disease)
- Smoking, illegal drug consumption
- Any gastrointestinal disease (Crohn's Disease, Celiac Disease, Inflammatory Bowel
Disease)
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