A Study of LY3303560 in Participants With Early Symptomatic Alzheimer's Disease



Status:Recruiting
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:60 - 85
Updated:4/5/2019
Start Date:April 30, 2018
End Date:October 8, 2021
Contact:There may be multiple sites in this clinical trial. 1-877-CTLILLY (1-877-285-4559) or
Email:ClinicalTrials.gov@lilly.com
Phone:1-317-615-4559

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Trial Summary
Trial Overview
Inclusion Criteria

Assessment of Safety, Tolerability, and Efficacy of LY3303560 in Early Symptomatic Alzheimer's Disease

The purpose of this study is to evaluate the safety and efficacy of a study drug that targets
an abnormal protein in the brain found in people with Alzheimer's Disease (AD).


Inclusion Criteria:

- Participants must have gradual and progressive change in memory function for >6
months.

- Participants must have a family member or close friend who is with you at least 10
hours per week and can attend study appointments.

Exclusion Criteria:

- Participants must not have significant neurological disease affecting the nervous
system, other than AD, that affects cognition or may affect completion of the study.

- Participants must not have serious or unstable illness that could interfere with the
analysis of the study or has a life expectancy <24 months.

- Participants must not have history of cancer within the last 5 years with the
exception of certain types of skin, cervical, prostate, and other cancers that are not
likely to recur or spread.

- Participants must not have serious risk for suicide.

- Participants must not have history of drug or alcohol use disorder within the last 2
years.

- Participants must not have multiple severe drug allergies

- Participants must not have HIV, Hepatitis B or Hepatitis C

- Participants must not be receiving gamma globulin (IgG) or intravenous immunoglobulin
(IVIG) therapy
We found this trial at
51
sites
Houston Methodist
Houston, Texas 77030
Principal Investigator: Joseph C Masdeu
Phone: 713-441-1150
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Tufts Medical Center
800 Washington St
Boston, Massachusetts 02111
(617) 636-5000
Principal Investigator: Tinatin Chabrashvili
Phone: 617-636-5000
Tufts Medical Center Tufts Medical Center is an internationally-respected academic medical center – a teaching...
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Renstar Medical Research
104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
Principal Investigator: John P. Nardandrea
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Ocala, FL
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Center for Neurosciences
2450 E. River Road
Tucson, Arizona 85718
520-320-2147
Principal Investigator: Michael A Badruddoja
Phone: 520-320-2140
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Lehigh Center for Clinical Research
Allentown, Pennsylvania 18104
Principal Investigator: Paul K. Gross
Phone: 610-820-0342
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JEM Research Institute
Atlantis, Florida 33462
Principal Investigator: Mark A Goldstein
Phone: 561-968-2933
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Atlantis, FL
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Julie B. Schwartzbard, MD, PA
21000 Northeast 28th Avenue
Aventura, Florida 33180
Principal Investigator: Julie Schwartzbard
Phone: 305-933-5993
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Aventura, FL
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Pharmasite Research
Baltimore, Maryland 21208
Principal Investigator: Alan M. Jonas
Phone: 410-602-1440
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Baltimore, MD
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The Memory Clinic
Bennington, Vermont 05201
Principal Investigator: Diana Michalczuk
Phone: 802-447-1409
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Bennington, VT
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Great Lakes Clinical Trials
Chicago, Illinois 60640
Principal Investigator: Jeffrey S. Ross
Phone: 773-275-3500
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Chicago, IL
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The Lindner Research Center
Cincinnati, Ohio 45219
Principal Investigator: Robert S Keyes
Phone: 513-585-1777
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Cincinnati, OH
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Medical Research and Health Education Foundation, Inc.
Columbus, Georgia 31909
Principal Investigator: Jonathan L Liss
Phone: 706-653-8455
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Columbus, GA
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Ohio State University Medical Center
Columbus, Ohio 43210
Principal Investigator: Douglas W. Scharre
Phone: 614-293-4969
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Columbus, OH
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Neurology Consultants of Dallas, PA
Dallas, Texas 75231
Principal Investigator: Duc Tran
Phone: 214-750-9977
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Dallas, TX
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Baylor AT&T Memory Center
Dallas, Texas 75219
Principal Investigator: Claudia Padilla
Phone: 214-820-7665
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Dallas, TX
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University of Cincinnati Health Neurology
3230 Eden Avenue
Dayton, Ohio 45417
Principal Investigator: Lawrence P Goldstick
Phone: 937-495-0000
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Dayton, OH
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Quantum Laboratories
Deerfield Beach, Florida 33064
Principal Investigator: Jose E De La Gandara
Phone: 954-786-7331
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Deerfield Beach, FL
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Brain Matters Research
Delray Beach, Florida 33445
Principal Investigator: Mark L Brody
Phone: 561-374-8461
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Delray Beach, FL
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Alexian Brothers Medical Center
Elk Grove Village, Illinois 60007
Principal Investigator: Ajay Sood
Phone: 847-981-3630
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Elk Grove Village, IL
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Pharmacology Research Institute
Encino, California 91316
Principal Investigator: DANIEL E. GROSZ
Phone: 818-705-7451
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Encino, CA
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Cognition Health
100 Eisenhower Drive
Fairfax, Virginia 22031
Principal Investigator: James L Bicksel
Phone: 703-505-8276
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Fairfax, VA
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Neuropsychiatric Research Center of Southwest Florida
Fort Myers, Florida 33912
Principal Investigator: Wendy Robinson Bond
Phone: 2399397777
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Fullerton Neurology and Headache Center
Fullerton, California 92835
Principal Investigator: Jack H. Florin
Phone: 714-738-0800
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Fullerton, CA
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Infinity Clinical Research, LLC
Hollywood, Florida 33021
Principal Investigator: Harvey Schwartz
Phone: 954-620-3340
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Josephson Wallack Munshower Neurology P.C
Indianapolis, Indiana 46256
Principal Investigator: Kristi George
Phone: 317-537-6056
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Indianapolis, IN
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Irvine Clinical Research Center
Irvine, California 92618
Principal Investigator: Elly R Lee
Phone: 949-753-1663
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Irvine, CA
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Rowe Neurology Institute
Lenexa, Kansas 66214
Principal Investigator: Vernon Rowe
Phone: 913-894-1500
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Lenexa, KS
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Pharmacology Research Institute
Los Alamitos, California 90720
Principal Investigator: David A Rosenberg
Phone: 714-827-3668
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Suburban Research Associates
Media, Pennsylvania 19063
Principal Investigator: Shivkumar Hatti
Phone: 610-891-9024
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Media, PA
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VIN - Victor Faradji
8940 North Kendall Drive
Miami, Florida 33176
Principal Investigator: Victor Faradji
Phone: 305-595-4041
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Miami, FL
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Boston Center for Memory
Newton, Massachusetts 02459
Principal Investigator: Paul R. Solomon
Phone: 617-699-6927
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Newton, MA
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Bioclinica
100 West Gore Street
Orlando, Florida 32806
Principal Investigator: Ira J Goodman
Phone: 407-210-1320
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Orlando, FL
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National Research Institute
2010 Wilshire Boulevard
Panorama City, California 91402
Principal Investigator: Parvin D Syal
Phone: 818-532-6880
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Panorama City, CA
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Kawartha Regional Memory Clinic
Peterborough, Ontario
Principal Investigator: Jennifer Ingram
Phone: 7057493906
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Banner Alzheimer'S Institute
Phoenix, Arizona 85006
Principal Investigator: William Burke
Phone: 602-829-9608
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Phoenix, AZ
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Progressive Medical Research
Port Orange, Florida 32127
Principal Investigator: Alexander J White
Phone: 386-304-7070
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Princeton Medical Institute
Princeton, New Jersey 08540
Principal Investigator: Jeffrey T Apter
Phone: 609-921-3555
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Princeton, NJ
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Butler Hospital
345 Blackstone Blvd
Providence, Rhode Island 02906
(401) 455-6200
Principal Investigator: Stephen P Salloway
Phone: 401-455-6403
Butler Hospital Founded in 1844, Butler Hospital is the state's only non-profit, free-standing psychiatric hospital...
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Raleigh Neurology Associates
Raleigh, North Carolina 27607
Principal Investigator: Bradley J Robottom
Phone: 919-782-3456
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Raleigh, NC
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Anderson Clinical Research
Redlands, California 92374
Principal Investigator: Donald L Anderson
Phone: 909-792-9007
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Redlands, CA
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Clinical Research Professionals, LLC
1040 North Mason Road
Saint Louis, Missouri 63141
Principal Investigator: Siddharth Kaul
Phone: 636-220-1200
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Pacific Research Network
San Diego, California 92103
Principal Investigator: Stephen Thein
Phone: 619-294-4302
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University of California at San Francisco
San Francisco, California 94143
Principal Investigator: Julio Rojas-Martinez
Phone: 415-476-6880
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Syrentis Clinical Research
Santa Ana, California 92705
Principal Investigator: John Duffy
Phone: 714-542-3008
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Santa Ana, CA
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The Cognitive and Research Center of NJ
Springfield, New Jersey 07081
Principal Investigator: Michelle Papka
Phone: 973-850-4622
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New England Institute for Clinical Research
Stamford, Connecticut 06905
Principal Investigator: Peter J McAllister
Phone: 203-914-1903
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Stamford, CT
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Brain Matters Research - Stuart
Stuart, Florida 34997
Principal Investigator: Mark L Brody
Phone: 561-374-8461
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Stuart, FL
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Infinity Clinical Research, LLC
Sunrise, Florida 33351
Principal Investigator: Richard Pete Singer
Phone: 9544758171
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Advanced Memory Research Institute of New Jersey
Toms River, New Jersey 08755
Principal Investigator: Sanjiv K Sharma
Phone: 732-341-9500
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Cotton O'Neil Clinic
Topeka, Kansas 66606
Principal Investigator: Michael Cox
Phone: 785-354-3680
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Topeka, KS
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PMG Research of Winston-Salem
1901 S Hawthorne Rd #306
Winston-Salem, North Carolina 27103
(336) 768-8062
Principal Investigator: Franklin Giles Crowell
Phone: 336-768-8062
PMG Research of Winston-Salem PMG Research of Winston-Salem, founded in 1979, occupies a 10,000 square...
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