Cardiac Function and Metabolism in Young Adults Born Premature (PET-MRI)



Status:Recruiting
Conditions:Women's Studies
Therapuetic Areas:Reproductive
Healthy:No
Age Range:18 - 35
Updated:10/7/2018
Start Date:September 20, 2017
End Date:August 2020
Contact:Jeni A Nestler, BS
Email:jnestler@medicine.wisc.edu
Phone:608-262-4233

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Trial Summary
Trial Overview
Inclusion Criteria

Cardiac Function and Metabolism in Young Adults Born Premature

The purpose of this research is to determine the effect of premature birth on later heart
function and metabolism.

The purpose of this study is to determine the effects of premature birth on cardiac function,
cardiac metabolism, and oxidative stress in a cohort of young adults born prematurely using
cardiac positron emission tomography/magnetic resonance imaging and mitochondrial respiration
studies.

Inclusion Criteria:

- National Lung Project Cohort only- birth weight <1500g and a gestational age <36 weeks

- Adults born preterm (Non-National Lung Project) only- gestational age ≤32 weeks OR
birth weight ≤ 3lbs 5oz

- Healthy Controls only- No personal history of known cardiovascular or pulmonary
disease

Exclusion Criteria:

- Metabolic Disorders that would affect Fludeoxyglucose uptake

- Contraindications to positron emission tomography and/or magnetic resonance imaging

- Pregnancy, if a female of child-bearing potential

- A personal history of Type I or Type II diabetes
We found this trial at
1
site
UW Madison
Madison, Wisconsin 53705
Principal Investigator: Kara N Goss, MD
Phone: 608-262-4233
?
mi
from
Madison, WI
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