Pre-emptive Analgesics in Orthodontic Treatment
| Status: | Completed |
|---|---|
| Conditions: | Chronic Pain |
| Therapuetic Areas: | Musculoskeletal |
| Healthy: | No |
| Age Range: | 12 - 59 |
| Updated: | 11/1/2018 |
| Start Date: | May 2, 2017 |
| End Date: | August 1, 2017 |
Effects of Pre-emptive Use of Combined Ibuprofen and Acetaminophen on Pain Control in Orthodontic Treatment
This study is designed to determine if the preemptive use of a combination of acetaminophen
and ibuprofen is more effective in reducing pain following orthodontic tooth movement when
compared to the use of acetaminophen and ibuprofen alone. Before their orthodontic
appointment, participants will be administered acetaminophen (650mg), ibuprofen (400mg), or
acetaminophen (650mg) + ibuprofen (400mg). Participants will be asked to record their pain
intensity using a numerical (0-10) visual analog scale (VAS) during rest, light biting, and
while chewing paraffin wax during the following time intervals: immediately following drug
administration, 6 hours after, the morning after, and the second morning after orthodontic
treatment.
and ibuprofen is more effective in reducing pain following orthodontic tooth movement when
compared to the use of acetaminophen and ibuprofen alone. Before their orthodontic
appointment, participants will be administered acetaminophen (650mg), ibuprofen (400mg), or
acetaminophen (650mg) + ibuprofen (400mg). Participants will be asked to record their pain
intensity using a numerical (0-10) visual analog scale (VAS) during rest, light biting, and
while chewing paraffin wax during the following time intervals: immediately following drug
administration, 6 hours after, the morning after, and the second morning after orthodontic
treatment.
Inclusion Criteria:
-Orthodontic patient presenting for orthodontic treatment
Exclusion Criteria:
- History of taking an analgesic in the past six hours
- Hypersensitivity to ibuprofen or acetaminophen
- Aspirin-sensitive asthma
- Renal or liver impairment
- History of GI bleeding or ulcers
- Cardiovascular disease, recent myocardial infarction, heart failure, or coronary
artery bypass graft surgery
- Currently taking antibiotics or other medications for a chronic systemic disease
- Bleeding disorder
- Pregnant or nursing
We found this trial at
1
site
Univ of Washington Founded in 1861 by a private gift of 10 acres in what...
Click here to add this to my saved trials
