DYNA EMBOLIZATION - Pilot Study of IV Dyna CT and CBV Imaging Techniques

There are common intracranial lesions that have increased vascularity that makes surgical
resection difficult. Embolization can improve the surgical procedure by easing the resection,
decreasing blood loss during surgical resection, and improving visibility of the surgical bed
during resection. Conventional intra-arterial (IA) angiography is the gold standard to
evaluating pathologies for embolization candidates, however the invasiveness of the procedure
(with associated risks), time requirements, and resource utilization of evaluating and
possibly embolization of these patients are precluding its widespread use.

Devising a test methodology that is quick, with less risk, and can accurately detect arteries
that are of value in embolizing these pathologies will improve the utilization as a screening
tool and will result in improved resource utilization that focuses only on those patients
that require embolization. Lastly, by correlating the Dyna CBV to surgical resection quality
(ease of resection, blood loss from surgical site), a non-invasive, controlled method to
evaluating embolization quality can be established to aid surgeons in pre-operative planning
as well as serve as a method of evaluating embolization materials designed for the blood
vessels associated with brain lesions.

The DynaCT technique is a fully FDA-approved application of the Siemens imaging system and
software. DynaCT is often performed during our angiographic and interventional procedures.
Neurointerventionists have begun to apply this technology within their practices, and the
investigators have selectively applied DynaCT for various clinical applications. However, at
this point the investigators have not incorporated the technology into clinical care for
patients with intracranial lesions.

Although DynaCT is an approved technology, there have been recent improvements in the
software performing the 3D reconstruction. These new features will be used in this study and
thus the investigators consider them to be "research scans."

Study patients will provide informed consent for the scan and the patients will not be billed
for the DynaCT portion of the procedure (only the standard of care conventional angiography).
The investigators have specifically chosen to image patients already undergoing conventional
angiography for surgical resection in order to have a direct comparison.

Inclusion Criteria:

1. Patients scheduled to have an intracranial lesion evaluated for possible surgical
resection.

Exclusion Criteria:

1. Patients with severe contrast allergies

2. Women who are pregnant or lactating.