Gender Differences of Neuroanatomical and Neurophysiological Correlates of Risk-proneness in Early Adolescents



Status:Not yet recruiting
Healthy:No
Age Range:10 - 12
Updated:5/25/2018
Start Date:May 14, 2018
End Date:December 31, 2018
Contact:Chanaka Kahathuduwa, MBBS PhD
Email:chanaka.kahathuduwa@ttu.edu
Phone:8068342451

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Gender Differences in Risk-proneness, Gratification Delay, Self-control, Self-efficacy, Executive Functions and Their Neurophysiological and Neuroanatomical Correlates in Early Adolescents

Risk-taking in early adolescence have has been found to be normative and even formative as it
might fulfill the youth's needs to experiment different sensations, make independent
decisions and learn from their consequences. Several theoretical models have suggested that
male and female adolescents differ in risk-taking as a product of individual/contextual
factors and neocortical functioning; however, the neurophysiological and neuropsychological
correlates of those differences continue to be underexplored. Informed by Evolutionary
Neuroandrogenic Theory, the investigators examine the links between gender, risk-proneness,
gratification delay, self-control, self-efficacy, executive functions and
neurophysiological-neuroanatomical correlates in early adolescents (age 10-12 years).
Participants (N=24; 50% females) will complete behavioral measurements on study constructs
and perform neuropsychological tests using fMRI scanning (e.g., Go/NoGo continuous
performance, stop-signal reaction time, NIH Cognition Battery, delay discounting). Female and
male groups will be compared on all outcome measures.


Inclusion Criteria:

- Early adolescents (age 10-12 years)

- Male and female

Exclusion Criteria:

- Gross impairment of vision or hearing that would prevent the participants from
performing neuropsychological tasks

- Inability to read and follow written instructions

- WISC-V IQ score of < 80

- Physical, neurological or concurrent psychiatric impairments that could affect
cognitive and motor functions

- Regular intake of medication that could alter visual, auditory, cognitive or motor
functions

- History of head injury that resulted in loss of consciousness / history of brain
surgery

- Current / past history of smoking and / or alcohol or drug abuse

- Absolute contraindications to undergo MRI
We found this trial at
1
site
Lubbock, Texas 79409
Principal Investigator: Elizabeth Trejos-Castillo, PhD
Phone: 806-834-2451
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mi
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Lubbock, TX
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