Laboratory Smoking of Marijuana "Blunts"

Inclusion Criteria:

- Currently living in Baltimore City or Baltimore County, MD;

- Able to read, understand, and sign informed consent;

- 18-55 years old;

- Currently smokes marijuana blunts;

- Designation of Medically Healthy for Research by the Study Physician; and

- Willing to abstain from illicit drug use other than marijuana for the duration of the
study.

Exclusion Criteria:

- BAC > 0.020% as measured by alcohol breathalyzer;

- Meets DSM-5 criteria for severe current or lifetime Cannabis Use Disorder;

- Meets DSM-5 criteria for any current Axis I disorder, other than current mild or
moderate Cannabis Use Disorder;

- Self-reported current desire to stop marijuana use;

- Self-reported current asthma, chronic obstructive pulmonary disease, hypertension,
cardiovascular disease or any other medical illness that precludes participation;

- Has difficulties with blood draws or poor venous access;

- History of blood donation in the past 30 days or receiving blood products within the
past 2 months prior to any experimental visit;

- Among females, current pregnancy or lactation or attempting to get pregnant, or at
risk of becoming pregnant;

- Acute illness which will require participant to be rescheduled