The Active Mind Study

The investigators will test the feasibility and acceptability of a combined mindfulness
training + aerobic training intervention, vs. either alone or none to improve cognitive
function in older adults with cognitive impairment. The investigators will also obtain
estimates of effect sizes (and confidence intervals) on cognitive function. Preliminary
analyses will be conducted to explore the mediating role of changes in aerobic capacity,
physical activity, vascular risk factors, and mindfulness skills. Assessments will be
conducted at baseline, 3-, and 6- months since baseline.

Inclusion Criteria:

1. Age ≥55

2. Being physically inactive (defined as not meeting current AHA recommendations for
physical activity, i.e., < 150 min of moderate-intensity aerobic activity per week OR
< 75 minutes of vigorous aerobic activity per week

3. Cognitive complaint defined as answering yes to the question "do you feel that your
memory or thinking skills have gotten worse recently?"

4. Fluency in English language

Exclusion Criteria:

1. Unwillingness/inability to provide informed consent

2. Contraindications to physical activity as per the participant's PCP assessment

3. Blood pressure >200/110

4. Severe depressive symptoms (defined as Hospital Anxiety and Depression Scale [HADS]
depression subscale scores >14)

5. Acute psychosis (from medical record)

6. Severe cognitive impairment (Mini-Mental State Examination [MMSE] score <24)

7. Recent hospitalization (< 6 weeks)

8. Current (at least once a month) mind/body practice (i.e., mindfulness meditation,
yoga, or tai chi)