Herbal Teas on Bone Health in an Osteopenic Population
| Status: | Recruiting |
|---|---|
| Conditions: | Osteoporosis, Gastrointestinal |
| Therapuetic Areas: | Gastroenterology, Rheumatology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 2/17/2019 |
| Start Date: | June 1, 2018 |
| End Date: | August 31, 2019 |
| Contact: | Paula A Witt-Enderby, PhD |
| Email: | wittp@duq.edu |
| Phone: | 412-396-4346 |
Assessing the Efficacy of Herbal Teas on Bone Health in an Osteopenic Population: OsTea
The project goal is to identify if herbal teas consumed 3 times per day over a period of
three months can improve these markers of bone health as well as improve QOL compared to
women taking placebo by increasing osteoblast activity, decreasing osteoclast activity,
increasing nocturnal melatonin levels and by decreasing CRP and cortisol levels. Our central
hypothesis is that these herbal teas will improve both objective and subjective measures of
bone health in an osteopenic population not taking this regimen by reducing osteoclast
activity and increasing osteoblast activity and by reducing stress and anxiety.
three months can improve these markers of bone health as well as improve QOL compared to
women taking placebo by increasing osteoblast activity, decreasing osteoclast activity,
increasing nocturnal melatonin levels and by decreasing CRP and cortisol levels. Our central
hypothesis is that these herbal teas will improve both objective and subjective measures of
bone health in an osteopenic population not taking this regimen by reducing osteoclast
activity and increasing osteoblast activity and by reducing stress and anxiety.
Inclusion Criteria:
- male or female with osteopenia (T-score between -1.0 and -2.5)
- at least 18 years of age
- must be willing to drink tea three times a day for 3 months
- must also be willing to come to the study location on 4 occasions (baseline, end of
month 1, end of month 2, and end of month 3),
- must also be willing to come to the study location to provide urinary, salivary and
fecal samples on 2 occasions (baseline and at the end of month 3),
- must also be willing to come to the study location to have their blood pressure taken
on 4 occasions (baseline, end of month 1, end of month 2, and end of month 3)
- must be willing to come to the study location to complete questionnaires on 2
occasions (baseline and at the end of month 3)
- must be willing to maintain daily diary for 4 months.
Exclusion Criteria:
- Women or men with osteoporosis
- Women or men with osteopenia due to hyperparathyroidism, multiple myeloma, metastatic
bone disease, chronic steroid use
- Women or men who are on any bone therapies (i.e. bisphosphonates, SERMs, hormone
therapy, teriparatide, and denusumab)
- Women or men with COPD
- Women or men who smoke
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